Scientists Hope To Create A ‘Stress Vaccine’ To Help With Anxiety And PTSD
9Inflammation conditions over the years increases with development
The increase of inflammatory disorders are directly associated with economic development and urbanization where such issues date back to 19th century Europe where diseases like hay fever were prevalent not among the poor but the rich. Hay fever was rare in farmers and more in urban educated people.
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10Farmers have better immunity because of animals
Recent studies have also shown that the farming environment has a protective effect on humans because of the contact with animals. In 1966, there was an explicit link suggested between lifestyle and autoimmune disease and allergic disorders. A few years later it was also pointed out that type 1 diabetes could be caused by autoimmune destruction of cells that secrete insulin in the pancreas. This is also increasing in some countries as the allergic disorders. Diseases like Crohn’s and ulcerative colitis have seen a rise in the 20th century in high income countries.
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11Vaccination with the bacteria decreased inflammatory conditions
Professor Lowry’s study found that Mycobacterium Vaccae is an environmental bacterium that has anti-inflammatory and stress resilience properties. Studies have also shown how vaccination with the bacteria prevented stress induced pro-inflammatory secretion from mesenteric lymph node cells, prevents stress-induced exaggeration of chemically induced colitis in a model of inflammatory bowel disease, and prevents stress-induced anxiety-like defensive behavioral responses.
Furthermore, immunization with M. vaccae induces anti-inflammatory responses in the brain. It also prevented stress-induced exaggeration of microglial priming. However, the study says that the molecular mechanisms of underlying anti-inflammatory effects of M. vaccae are not known.
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12Conclusion
Lowry’s research concluded that while they found that the fatty acid in the bacteria Mycobacterium Vaccae should be evaluated and studied for its effects on stress-induced exaggeration of peripheral inflammatory signaling, central neuro-inflammatory signaling, and anxiety- and fear-related defensive behavioral responses.
Now we know why our older generation was more immune to colds and coughs in comparison with children of today. It’s because children today don’t play outside anymore.
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