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5What was the hygiene hypothesis?
The hygiene hypothesis first began with the simple suggestion that when a person is exposed to germs like dirt, it may be of some help. This is why is also regarded that when children are exposed to dirt, it increases their immunity. This is in extension of the age-old theory that microbes and humans have evolved together and there are some microbes that are beneficial instead of harmful and which can keep us healthy.
6Humans evolved with bacteria and some of it was helpful
Lowry says “The idea is that as humans have moved away from farms and an agricultural or hunter-gatherer existence into cities, we have lost contact with organisms that served to regulate our immune system and suppress inappropriate inflammation,” Lowry said in his research.
The age-old theory became to be known as the hygiene hypothesis in 1989 after observing in young adults a history of hay fever was inversely related to the number of siblings (especially older male siblings) in their family when they were 11 years old.
7Inflammation is a protective mechanism of our bodies for the recovery process
Inflammation is a protective mechanism of our bodies and is usually accompanied by pain, swelling, redness or even fever. This condition evolved in order for the body to remove the infectious tissue and then start the healing process. There are various negative mechanism also involved to stop this process which target the gut content and terminate the inflammation if it is not required.
8What happens when inflammation process fails?
Sometimes the mechanisms responsible for inflammation fail and the prevalence of this has been seen surprisingly not in developing countries but high income countries instead where there has been an increase in chronic inflammation disorders and allergies like autoimmune disease, inflammatory bowel disease because of inappropriate inflammatory responses that are not terminated.